20 - Hormones and metabolism: Unlocking the science with Professor Franck Mauvais-Jarvis
The Dr Louise Newson Podcast
Dr Louise Newson
4.8 • 798 Ratings
🗓️ 12 August 2025
⏱️ 31 minutes
🧾️ Download transcript
Summary
“I don’t understand why we’re not shouting this from the rooftops, a simple medicine, a natural hormone, that can reduce the risk of both diabetes and breast cancer. That’s incredibly important, isn’t it?”
This week, Dr Louise Newson is joined by Franck Mauvais-Jarvis, Professor of Medicine at Tulane University and an endocrinologist specialising in metabolism.
In this episode, they dive deep into the science behind oestradiol’s crucial role in maintaining a healthy metabolism, reducing inflammation throughout the body, and supporting memory and cognition.
Professor Mauvais-Jarvis explains how improving mitochondrial function, often referred to as the “powerhouse of the cell,” boosts metabolism and helps prevent metabolic diseases such as diabetes. He also highlights the vital, often overlooked role of testosterone in women’s health.
Together they address common misconceptions stemming from the 2002 Women’s Health Initiative (WHI) study and set the record straight on the benefits of body-identical hormones.
Be sure to check out Professor Franck Mauvais-Jarvis’s book, Principles of Precision Hormone Therapy: Healthy Aging and Prevention of Chronic Disease, which presents cutting-edge scientific data and insights from leading experts, including Dr Louise Newson, on the vital role of hormone optimisation in healthy aging.
Available to watch on YouTube
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Disclaimer
The information provided in this podcast is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition. The views expressed by guests are their own and do not necessarily reflect the views of Dr Louise Newson or the Newson Health Group.
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Transcript
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| 0:00.0 | Some of you might know already, but this podcast has been nominated by the British podcast awards for the listeners' choice. |
| 0:08.4 | So we really need your votes because it would be such an honour and thrill to do well in this. |
| 0:13.5 | So if you go to the show notes and click on the link, it won't take you long. |
| 0:17.7 | Please just vote for us. Thank you so much. |
| 0:25.5 | So on this podcast, I've got a really good friend and colleague, Professor Frank Movey Jarvis, from US. He's a professor of endocrinology |
| 0:32.3 | with a special interest in metabolism. So we talk a lot about the role of hormones, estradi, especially, but also testosterone in metabolism. So we talk a lot about the role of hormones, estradiol especially, |
| 0:39.5 | but also testosterone in metabolism, in reducing incidence of diabetes. And we talk about |
| 0:45.8 | mitochondria, the powerhouse of ourselves and how that can improve in the presence of Easter dial. |
| 0:51.9 | So enjoy it. |
| 0:57.4 | So Frank, it's really exciting. |
| 1:00.0 | I feel like I've known you for quite a long time, |
| 1:02.0 | but I can't remember when I first... I think I reached out to you, didn't I? |
| 1:03.9 | Because I'd read one of your great papers. |
| 1:06.6 | It was at the beginning of COVID. |
| 1:08.4 | Yeah, and in fact, I was reading a paper the other night and I read |
| 1:11.8 | it out to my husband, the line, because it was saying there is good evidence that estrogen |
| 1:17.8 | protected people from COVID. And I was saying to him, why wasn't anyone listening at the time? |
| 1:24.6 | Like, it was so frustrating. But what I love about your work is that you're |
| 1:28.6 | interested in the metabolic processes that occur in the body. And there are very few people, |
| 1:34.5 | really, I think, that understand the importance of hormones, Easterdial progesterone and testosterone |
| 1:40.4 | on improving our metabolism and reducing inflammation. |
| 1:45.0 | So can you just tell me a bit about your background and why you're doing what you're doing |
... |
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