4.8 • 216 Ratings
🗓️ 4 December 2025
⏱️ 83 minutes
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| 0:00.0 | When Amazon had hit $5 billion in market cap, |
| 0:05.0 | and it's probably going to sustain this revenue growth rate |
| 0:10.0 | in the 20 to 30% range for 20 years. |
| 0:14.0 | Nobody believed that. |
| 0:16.0 | Well, that's exactly what happened. |
| 0:18.0 | The first whole human genome was sequenced in 2003. The cost to |
| 0:23.6 | do so was $2.7 billion, and it took 13 years to get there. We were not ready for prime time. |
| 0:33.6 | That 2.7 billion to sequence one human genome is down to $200. That 13 years is down to a couple of hours. |
| 0:43.3 | You know, we have never seen this amount of technologically enabled disruption in history. |
| 0:50.3 | You have to go back to the late 1800s, early 1900s, internal combustion engine, |
| 0:55.1 | telephone, electricity to see a true technology revolution. What regulation would you like |
| 1:01.8 | to see around AI, if any? To regulate AI right now would have been like regulating the internet |
| 1:10.4 | in the late 80s and early 90s before we really |
| 1:13.7 | understood its ramifications safety security is paramount but we've seen other industries |
| 1:22.9 | regulated out of business and a really good one is nuclear power. Regulation really can hold |
| 1:31.5 | innovation back. When we interviewed Howard Marks in March of this year, he observed it's the pioneers |
| 1:37.8 | who get the arrows. And what I've learned is that in investing, the main way you gain unusual |
| 1:43.2 | success is by doing things that |
| 1:45.2 | other people don't want to do. It's hard to achieve singular success by joining the herd. |
| 1:51.0 | Well, many consider a 21st century investment pioneer to be Kathy Wood. She embraces disruptive |
| 1:57.8 | innovation themes early, has faced intense criticism during large drawdowns, |
| 2:02.7 | has reshaped ETF thinking, and is characterized as bold, influential, controversial, and |
... |
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