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Core IM | Internal Medicine Podcast

#169 Immune Checkpoint Inhibitor Adverse Events 2.0: 5 Pearls Segment

Core IM | Internal Medicine Podcast

Core IM Team

Mental Health, Education, Health & Fitness, Medicine

4.81K Ratings

🗓️ 8 January 2025

⏱️ 45 minutes

🧾️ Download transcript

Summary

How do you differentiate immune checkpoint inhibitor-related adverse events aka IrAEs from other conditions like infection? Join as we go through pneumonitis, colitis, dermatitis and endocrinopathies due to immune checkpoint inhibitor toxicity!

Transcript and Show Notes

ICIs & IrAEs 101 Episode

Sponsor:


Get CME-MOC credit with ACP!

Timestamps:

(03:14) | Pearl 1

(13:34) | Pearl 2

(24:42) | Pearl 3

(30:34) | Pearl 4

(35:21) | Pearl 5


Tags: CoreIM, Internal Medicine, ClinicalPearls, Skin Toxicity, Medical Education, IMCore, oncology, hospitalist, physician assistant, nurse practitioner, medical student



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Transcript

Click on a timestamp to play from that location

0:00.0

Hi, everyone. We are thrilled to have Glass Health as our sponsor. Let's hear from Derek Paul,

0:04.5

the co-founder and CEO of Glass Health, which is a platform that empowers clinicians with the best-in-class

0:09.3

AI for clinical decision support. At Glass, one of the things we're most excited about is trying

0:15.0

to help the provider navigate clinical information and clinical literature to draft assessment

0:20.8

and plan. So actually going and

0:23.7

navigating an article that would be similar to an up-to-date article that has the peer-reviewed clinical

0:29.8

guidelines and or the large language model to say, okay, next steps are to order this test

0:36.3

to advance our understanding this problem

0:38.3

diagnostically or here's the standard of care treatment.

0:42.3

And I think what's important in all of this is that the healthcare provider is still very much

0:46.7

in the driver's seat and very much supervising the large language model.

0:50.6

In the way that you might supervise a medical student. You're sort of in an edit in a

0:54.5

test mode, but I think that's going to have huge benefits on efficiency. And we will link to that

1:00.6

assessment and plan feature in the show notes. Good news is that you can get one month free access

1:05.4

to Glass Pro using the promo code Coram. We'll link it in our show notes. And with that, let's get

1:10.1

into the episode. And as a bonus, if you have Glass Pro our show notes. And with that, let's get into the episode.

1:15.4

And as a bonus, if you have Glass Pro and share your code, you and a friend can get an additional 30 days free. You have to think a little bit like a Bunmar transplant doctor. And they have

1:22.5

learned an amazing instinct for how inflammation and irritation results in misbehavior of the transplanted

1:30.1

immune system. So you have to have a little bit of paranoia and you have to look for subtle

1:34.1

things when dealing with checkpoint inhibitors and dealing with the immune system. Anytime

1:37.6

there's something on a scan that doesn't make sense, you kind of need to explain it. And anytime

1:41.8

someone doesn't get better, you kind of need to explain it.

...

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