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The Melanie Avalon Biohacking Podcast

#146 - Dr. Rick Johnson: Fructose & Obesity, The Survival Switch, Salt & Weight Gain, Stimulating Fat Production, Uric Acid, The Polyol Pathway, Metabolic Syndrome, And More!

The Melanie Avalon Biohacking Podcast

Melanie Avalon

Alternative Health, Nutrition, Health & Fitness

4.7655 Ratings

🗓️ 20 May 2022

⏱️ 91 minutes

🧾️ Download transcript

Summary

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/fructose 2:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 10:50 - Beginning Of Fructose Research 14:30 - How Sugar Can Cause Weigh Gain Independently Of Caloric Intake 17:30 - Leptin Resistance 23:10 - Defining Glucose, Sucrose, And Fructose 26:55 - "Tasteless" Mice 28:00 - Craving Sugar  31:20 - 5 Great Tastes 33:00 - Artificial Sweeteners 34:00 - Blocking The Fructokinase In The Liver 36:00 - How Fructose Tricks The Body 42:10 - How Fructose Uses Glucose To Create Fat 50:00 - Polyol Pathway 51:40 - Stress & Dehydration 53:50 - Salt 1:00:30 - How Hibernation Mimics Metabolic Syndrome 1:04:30 - Evolutionarily, Where Did This Start? 1:07:45 - The Natural Fasting Cycle 1:08:30 - The Role Of Fructose In The Cells, AMPK, And AMPD 1:16:00 - What Happens When You Combine Starvation With The AMPK Pathway? 1:21:00 - Starvation Mode 1:24:30 - What About Whole Fruit? The Role Of Vitamin C

Transcript

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0:00.0

So we think that the craving is linked with the gut and that there's a gut brain pathway.

0:06.0

The liver though is the place where the action is.

0:10.0

The glucose goes up in the liver and in the blood and that triggers the production of fructose.

0:15.0

So now you have another mechanism that could drive obesity, not just insulin, but fructose.

0:22.4

Which organ is responsible for what affects the liver?

0:26.9

That's the place that drives whether or not you're going to get fat or die better.

0:31.5

Welcome to the Melanie Avalon Biohacking Podcast, where we meet the world's top experts to explore the secrets of health,

0:40.2

mindset, longevity, and so much more. Are you ready to take charge of your existence and biohack

0:47.1

your life? This show is for you. Please keep in mind. We're not dispensing medical advice

0:52.9

and are not responsible for any outcomes you may

0:55.7

experience from implementing the tactics lying herein. Are you ready? Let's do this.

1:04.1

Welcome back to the Melanie Avalon biohacking podcast. Oh my goodness friends, I am so, so excited

1:10.5

about today's episode. I love Rick Johnson.

1:13.8

I love his work. I love what he's doing. He's also just the kindest, most intelligent,

1:19.6

savvy human being. I am so honored to finally connect with him. I have been a fan of his work for

1:24.9

years, honestly years. And so to have him on the show now and become friends with him is just so wonderful.

1:30.4

And just so you know how much I really appreciate his work, we don't normally have guests

1:34.8

on the Intrament Fasting podcast.

1:36.3

And I invited him to come back on that show because that's how valuable I think his work is.

1:41.7

We dive deep, deep, deep into so many things in today's show, the role

1:46.0

of fructose and uric acid in health, the metabolism, insulin, what really is behind weight gain,

1:52.9

and so much more. I think you guys will love it. And as we do dive deep, definitely check out

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