Good-A, Dominic Barfield here, and this is the RVC Clinical Podcast.

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So again, we're not in the studio.

We're recording remotely and joining Brian and myself.

We're talking to Associate Professor Karen Humb, one of our wonderful emergency and critical care team members, as well as the lead of the

Transfusion Medicine Service at the RBC, and we thought we'd talk about xenotransfusion.

So thank you very much, Karen, for joining us.

Thank you for asking, Don.

Well, you know, it was no difficulty considering we share an office, although I did email you for this

request. So I suppose xenot transfusions, have they been around a while, Karen? Yes. So,

I mean, xenotransfusions in the true sense is transfusing one species blood to another. And when we think

about them, generally we think about dog blood to cats, because that's probably the major

use you'd be thinking of, the time when they're most convenient. But actually, the first

xenotransfusions were from animals to humans because of ABO incompatibilities.

They knew that before they'd worked exactly how that system worked.

They knew that if you gave some human's blood to another human, it could lead to sudden death due to anaphylactic

reaction, or an acute hemaltic transfusion reaction. So they,

...