Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions.

This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy.

This podcast contains general information for educational purposes only. This is not

professional advice and should not be used in lieu of obtaining advice from a qualified

health care provider. And now on to the show. Welcome to Helix Talk episode 121. I'm your

co-host Dr. Kane. And I'm Dr. Patel. And in today's episode, but wait,

there is more, we're going to talk about unusual warfarin interactions. The emphasis of today's

episode is to talk about a handful of drug interactions that are relevant for warfarin, some of which

are commonly known, like the green leafy vegetables, but what about some of the other food

items that are out there that do have a good amount of vitamin K in them that aren't green and leafy?

So we're going to talk about a variety of drug interactors that are important for clinicians

to know when it comes to warfarin or cummiden.

And some of the audience may wonder, why are we still talking about Warfarin, right?

Because we have DOACs and a lot of patients who were on Warfarin before have been transitions

to DOACs.

However, there are still some group of patients still remain on Warfarin.

These are your valvular atrial fibrillation patients, those who have mechanical heart valve,

poor renal function, poor liver function.

Maybe they have active liver disease, their post-transplant.

They have certain thromophilias where, you know, DOACs have not been studied yet.

Or maybe they are taking those super SIP-3-A-4 interacting drugs where DOACs are kind of borderline contraindicated, like phantotone, for example.

So that's where the use of warfarin comes in.

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