4.8 • 4.4K Ratings
🗓️ 31 August 2020
⏱️ 80 minutes
🧾️ Download transcript
Not too long ago nobody carried a mobile phone; now almost everybody does. That’s the kind of rate of rapid progress we’re seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term “gene editing.” We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.
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Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.
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0:00.0 | Hello everyone, welcome to the Mindscape Podcast. |
0:03.0 | I'm your host Sean Carroll. |
0:04.6 | And I'm sure that you've all heard the excitement, |
0:07.5 | the worries, the news overall over the last few years |
0:11.0 | about gene editing, the possibility of editing human genes |
0:15.0 | at a very detailed level, not to mention plant |
0:17.7 | and animal genes, of course. |
0:19.3 | Today's guest, Fido Urnov, is actually not just |
0:21.8 | one of the world's experts, he coined the term gene editing |
0:25.0 | and he's been active in the field since the beginning, |
0:26.9 | so he knows what he's talking about. |
0:29.0 | And I know that as well as prospects for curing diseases |
0:32.2 | and stuff like that, there are worries about, you know, |
0:35.2 | it would be good to cure diseases using gene editing, |
0:38.8 | but what if someone made super soldiers |
0:41.0 | and they became bad like the red skull instead of good, |
0:43.8 | like Captain America, wouldn't that be bad? |
0:46.4 | So at the end of this interview, I asked Fiodora, |
0:49.0 | I said, you know, as responsible as we might want to be, |
0:53.4 | as scientists, as countries, as international regulatory |
0:57.2 | agencies, isn't it coming to the point |
0:59.8 | where this is almost too easy and almost anyone |
... |
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