Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions.

This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy.

This podcast contains general information for educational purposes only. This is not professional

advice and should not be used in lieu of obtaining advice from a qualified health care provider.

And now on to the show.

Welcome to episode 95. I'm your co-host, Dr. King. I'm Dr. Schumann. And I'm Dr. Patel.

And today's title of our episode is the ultimate guide to Ns, an in-depth, Dr. Kane. I'm Dr. Schumann. And I'm Dr. Patel. And today's title of our episode is the

ultimate guide to inseds, an in-depth drug class review, where we'll be talking about inseds,

everything from when are they indicated, what are some of the toxicity profiles of those,

and really what are some of the differences between a drug class that has over 20 different

drugs in its category.

So if for our listeners, setting up the background will be nice and so we can talk about maybe how the ensigns actually work and looking at the detail pharmacology.

So as we know, it's an anti-inflammatory, works on the inflammatory pathway that triggers

the release of errocodonic acid.

And this erocodonic acid is then further acted by cyclooxygenase enzymes. And eventually,

they are then converted into prostaglandins, prostaclyans, and thromoxons. And these are compounds.

They play an important role in, you know, mounting fever, causing painoxons. And these are compounds that play an important role in mounting fever,

causing pain and inflammation. But they are also important in certain non-inflammatory pathways

to carry out daily functions of bodily organs. Right. And there are really two different types of

Cox enzymes. So you have Cox 1 or psycho-oxygenase 1. That's the one that's always expressed as

part of your routine cellular maintenance and function. One of the big things we know about that

is responsible for the protection of the gastric epithelial cell. So that's one of the reasons why

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