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FoundMyFitness

#089 Why Exercise Intensity Matters for Longevity | CrossFit for Health 2024

FoundMyFitness

Rhonda Patrick, Ph.D.

Fitness, Depression, Foundmyfitness, Timferriss, Sleep, Diet, Longevity, Ketosis, Rhondapatrick, Kevinrose, Domdagostino, Health, Sauna, Nutrition, Medicine, Fasting, Healthspan, Mattwalker, Coldexposure, Lifeextension, Health & Fitness, Exercise

4.85.5K Ratings

🗓️ 8 April 2024

⏱️ 51 minutes

🧾️ Download transcript

Summary

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I recently had the privilege of presenting at the CrossFit Health Summit, where I explored a constellation of factors contributing to longevity. In this context, I placed a special emphasis on the pivotal role of vigorous exercise throughout life.

In this episode, I discuss:

  • (03:12) Why "below normal" cardio may be a great starting point (for adding years to your life)
  • (05:07) The simple math of 45 days of life extension (per 1 mL/kg/min VO2max)
  • (05:15) Is there an upper limit to the longevity benefits of VO2 max?
  • (06:12) Why poor cardiovascular fitness is nearly as bad as a chronic disease
  • (06:52) Why zone 2 training may not improve VO2 max (for some people)
  • (08:08) Protocols for improving VO2 max quickly
  • (09:10) How to estimate VO2 max in 12 minutes (without a lab)
  • (10:07) What it takes to reverse 20 years of heart aging
  • (12:41) Blood pressure benefits of vigorous exercise
  • (13:10) The role of blood pressure in dementia
  • (13:29) The BDNF brain benefits of high-intensity exercise
  • (14:05) The signaling role of lactate production by muscle
  • (16:13) How training effortfully improves focus & attention
  • (17:04) Protocols for maximizing BDNF from training (HR training targets and duration)
  • (17:23) Anti-cancer effects of vigorous exercise
  • (18:11) Why shear stress kills circulating tumor cells — an experiment in three cell lines
  • (18:33) Why reducing circulating tumor cells likely greatly increases survival
  • (19:00) What if you exercise in short bursts all day long?
  • (20:06) Why "exercise snacks" are a crucial pre- and post-mealtime activity
  • (20:49) The best ways to improve mitochondrial biogenesis — and metabolism
  • (21:47) The mortality benefits of breaking up sedentary time
  • (26:17) Why the protein RDA is too low (and the flawed experiments that lead to that)
  • (27:19) How much protein is needed for muscle?
  • (29:07) Does omega-3 reduce muscle atrophy?
  • (30:41) Why we should lift for aging and to prevent the 8% per decade decline of muscle
  • (32:03) Is lifting heavy necessary for gaining muscle?
  • (33:06) What the sauna has in common with exercise
  • (34:45) Does the sauna enhance the benefits of exercise?
  • (36:44) How heat shock proteins prevent plaque aggregation & slow muscle atrophy
  • (38:23) Can sauna after resistance training boost hypertrophy?
  • (39:06) Sauna parameters (temperature, duration, frequency, & humidity)
  • (39:59) Comparing traditional saunas to infrared
  • (40:59) Are hot baths a valid sauna alternative?
  • (42:15) Audience Q&A
  • (42:19) Is EPA or DHA responsible for omega-3's effects on disuse atrophy?
  • (43:53) Are endurance athletes at risk for cardiovascular injury?
  • (44:57) What mechanisms are responsible for sauna's benefits?
  • (47:08) Is a sauna temperature above 200 °F too hot?
  • (49:31) My recommended sauna temperature & duration

Watch this episode on YouTube

Show notes are available by clicking here

Transcript

Click on a timestamp to play from that location

0:00.0

For many people, cross-fit is practically synonymous

0:02.7

exercise as a concept.

0:04.9

It is self-evident that they have mastered the art of making

0:07.3

effortful, challenging training coachable.

0:09.7

And they've been doing it for quite a while,

0:11.1

making cross-fit programming one of the many

0:12.9

great options for someone starting out and wanting to tap into the

0:15.8

biologically unique benefits of vigorous intensity exercise. My athletic

0:20.0

background is that of a runner, not a crossfitter. However, working with a coach, I am finding it extremely

0:25.6

valuable to add compound multi-joint lips and many other hallmarks of cross-fit style programming

0:31.1

to my growing repertoire.

0:33.0

Whatever type of training you do, I encourage you to find something that can engage you in a way

0:37.1

that you find challenging and that you can commit to regularly.

0:40.9

In short, I encourage you to put in the effort and sweat.

0:44.8

The episode you're about to listen to is a keynote presentation I gave at the CrossFit

0:48.8

Health Summit in Austin, Texas last February.

0:51.8

There are accompanying slides on YouTube but they are not

0:54.1

necessary for the information as presented. In this presentation I cover

0:58.2

why below normal cardio may be a great starting point for adding years to your life

1:01.9

and the surprisingly simple math for

1:03.8

adding 45 days to your life with incremental V.O.2. Max improvements.

1:08.0

What protocols are scientifically proven to quickly improve V.O.2 Max and how to estimate your

...

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