077 - The Use of Investigational Drugs in an Outbreak: Separating Science and Politics With Hydroxychloroquine and COVID-19

Public Health On Call

The Johns Hopkins Bloomberg School of Public Health

Medicine, News, Health & Fitness

4.6 • 644 Ratings

🗓️ 22 May 2020

⏱️ 17 minutes

🔗️ Recording | iTunes | RSS

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Summary

The use of investigational drugs during a public health crisis is not new. In 2014, Dr. Linda Mobula had experience administering an untested drug during the Ebola response in West Africa. Mobula talks to Dr. Josh Sharfstein about how the technical framework that came out of that process could have been used to provide guidance for investigational drugs in COVID-19, and how political figures created a global push for hydroxychloroquine.

Transcript

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0:00.0	Welcome to Public Health On Call, a new podcast from the Johns Hopkins Bloomberg School of Public Health.
0:12.7	Our focus is the novel coronavirus.
0:15.2	I'm Josh Sharfstein, a faculty member at Johns Hopkins, and also a former secretary of Maryland's health department.
0:21.6	Our goal with this podcast is to bring evidence and experts to help you understand today's
0:26.9	news about the novel coronavirus and what it means for tomorrow.
0:30.5	If you have questions, you can email them to public health question at jhh.edu.
0:36.3	That's public health question at jh.h. That's public health question at jh.edu for future podcast episodes.
0:43.0	Today I speak with Dr. Linda Mobula, a physician affiliated with the Division of General
0:48.0	Internal Medicine at Johns Hopkins.
0:50.2	Dr. Mobula first became interested in the use of investigational drugs during public health
0:55.5	crises when she worked in West Africa fighting the Ebola outbreak.
1:00.4	She recently returned from New York, where she volunteered to take care of COVID patients.
1:05.5	We speak about the investigational drug hydroxychloroquine and COVID-19.
1:10.4	This interview was recorded before President Trump disclosed that he takes hydroxychloroquine in COVID-19. This interview was recorded before President Trump disclosed
1:12.6	that he takes hydroxychloroquine.
1:15.6	Let's listen.
1:16.6	Dr. Mabula, thank you so much for joining me.
1:20.6	Now, I know that you are no stranger to the use of
1:22.6	investigational drugs in the middle of a public health crisis.
1:26.6	Can you tell me a little bit about your experience with the Ebola outbreak?
1:31.0	Thank you, Dr. Sharstein, for having me.
1:33.4	I participated in the Ebola response in West Africa in 2014,
	...

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