077 - PE: Not Just a Class in Junior High -- Top 5 Clinical Pearls about Pulmonary Embolism
HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
Sean P. Kane, PharmD, BCPS
5 • 644 Ratings
🗓️ 24 April 2018
⏱️ 32 minutes
🧾️ Download transcript
Summary
In this episode, we discuss five clinical pearls about pulmonary embolism ranging from PE diagnosis, classification, and treatment. We specifically examine when and how alteplase is given for PE and its use with concurrent anticoagulation.
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions. |
| 0:11.0 | This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy. |
| 0:17.0 | This podcast contains general information for educational purposes only. This is not |
| 0:22.0 | professional advice and should not be used in lieu of obtaining advice from a qualified health |
| 0:26.3 | care provider. And now on to the show. Welcome to Helix Talk episode 77. I'm your |
| 0:33.8 | co-host Dr. Kane. I'm Dr. Schumann. And I'm Dr. Patel. And the title of today's episode is PE, not just a class in junior high, top five clinical |
| 0:41.9 | pearls about pulmonary embolism. |
| 0:43.8 | So today we're talking about some clinical pearls related to PE or pulmonary embolism that |
| 0:48.0 | every pharmacist should know. |
| 0:49.8 | And it's going to range from the diagnosis of PE to its different classification and the treatment |
| 0:55.0 | and we're going to focus a little bit more on not the anti-coagulation so much but the |
| 0:58.9 | Altaplase used, that's the clot buster. |
| 1:01.8 | So just to kind of start things off, I think before we get to those five clinical pearls, |
| 1:05.6 | we first have to just set the stage for those that may be a little bit less familiar with |
| 1:09.8 | pulmonary embolism or PE. |
| 1:11.6 | Sure, so a PE pulmonary embolism is a blood clot in the pulmonary artery. |
| 1:16.6 | It includes blood flow to the lung, which is obviously a bad thing. |
| 1:19.6 | So we know that less blood flow to conduct oxygen exchange in the alveoli leads to hypoxia. |
| 1:24.6 | Right side of the heart has trouble pumping blood through the pulmonary circuit, so left side of the heart doesn't get much blood as well, so leads to hypoxia, right side of the heart has trouble pumping blood through the |
| 1:27.6 | pulmonary circuit. So left side of the heart doesn't get much blood as well. So beyond the |
| 1:31.3 | hypoxia, we've also got hypotension. Yeah, so you reduce your output basically and that leads to |
| 1:37.3 | lower blood volume leading to the hypotension. And it turns out that all of your cells in your body |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Sean P. Kane, PharmD, BCPS, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Sean P. Kane, PharmD, BCPS and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2025.