Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions.

This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy.

This podcast contains general information for educational purposes only. This is not professional

advice and should not be used in lieu of obtaining advice from a qualified health care provider.

And now on to the show.

Welcome to Helix Talk episode 75. I'm your co-host Dr. Kane. I'm Dr. Schumann. And I'm

Dr. Patel. And during the previous episode, we talked about perioperative management of anticoagulants

and antipatlet.

That was number 74.

We're continuing the same talk in this episode as well.

So I think we ended somewhere in talking about what to do with specific anticoagulants.

Let's move to what to do

in regards to antiplatelets because these also require some holding around the procedure time

because of increased risk of bleeding. And, you know, the most common antiplatelet that should come

to everyone's mind is aspirin. What's unique about aspirin is even at doses as low as something like

50 milligrams a day, you can get a good amount of anti-platelet effect. And really, that's where

the sealing effect is. So giving 325 or even 650 of aspirin gives you no more anti-platelet effect.

So even that baby aspirin, which is probably a misnomer because we don't use it in babies,

even that baby aspirin dose gives you profound antiplatelet effect. Yeah, so the recommendation

about aspirin around the procedure is going to be irrelevant of the doses of the aspirin itself.

We do know that there is longer inhibition of platelets with aspirin. So the recommendations

are really divided based on what's the patient cardiovascular risk? Because as you said, Dr. Kane,

...