#064 Dr. Michael Snyder on Continuous Glucose Monitoring and Deep Profiling for Personalized Medicine

FoundMyFitness

Rhonda Patrick, Ph.D.

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4.8 • 5.5K Ratings

🗓️ 27 May 2021

⏱️ 75 minutes

🔗️ Recording | iTunes | RSS

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Summary

Michael Snyder

Dr. Michael Snyder is the director for the Center for Genomics and Personalized Medicine at Stanford and a pioneer and advocate of "deep profiling." Deep profiling seeks to apply intelligent analysis to large data sets to yield specialized clinical insight, ranging from common consumer-grade wearables like Apple Watches to whole-body MRI, continuous glucose monitoring, and metabolomics.

In this episode, we discuss:

00:00:00 - Introduction
00:12:51 - Continuous glucose monitor use in people without diabetes
00:31:04 - A smartwatch helped diagnose Dr. Snyder's Lyme disease
00:34:00 - Predicting other illnesses with smartwatches
00:40:41 - Detecting airborne pollutants in the exosome
00:51:04 - Genetics and metabolism tell us our Ageotypes
00:58:05 - Exercise is most important for longevity
01:03:11 - Dr. Snyder's lifestyle habits

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Transcript

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0:00.0	Today's episode features a self-confessed believer in the philosophy that more data is usually better,
0:07.3	an enthusiast for all things wearable technology, including and particularly continuous glucose monitors,
0:14.2	but also sleep trackers, fitness trackers, ex-posome trackers, and more.
0:18.8	In addition, he is the chairman of the Department of Genetics and Director of the Center for Genomics and Personalized Medicine at Stanford University.
0:27.8	That man is Dr. Michael Snyder.
0:30.8	Today, we talk a lot, including how some of these technologies, such as the more lab clinical analytic varieties like measuring metabolomics, transcriptomics, proteomics, and genomics, might change medicine for the better,
0:45.2	making it more personal, making it more preventative.
0:48.8	Many of you, I'm sure, will be particularly interested in our discussion in the overall utility of continuous glucose monitors, or CGMs, from a preventative medicine standpoint.
0:58.8	While CGMs like the DEXCOM and the freestyle library are still considered a medical product, and for the most part are prescribed under the care of a physician,
1:06.8	they have been fairly commoditized with companies like NutriSense, January AI, and Levels, making them widely and easily available to lifestyle optimizers through a physician network,
1:16.8	usually around a couple hundred dollars per month.
1:19.8	In this episode, Dr. Snyder and I discuss how his genomic analysis revealed he was at risk for type 2 diabetes, and how ultimately this coincided with an eventual diagnosis.
1:30.8	How some of Dr. Snyder's data suggests that 9 out of 10 people with pre-diabetes are unaware they have it.
1:36.8	This is important because even pre-diabetes can be clinically relevant.
1:40.8	However, a person's blood glucose response to a specific type of food can drastically differ from another person's.
1:46.8	How Dr. Snyder used wearable devices to help diagnose his Lyme disease?
1:51.8	How Dr. Snyder's ongoing study used wearable devices to help identify elevated heart rate as one of the first symptoms in many illnesses including COVID-19?
2:01.8	How smart watches that can detect heart rate variability may be able to help detect some heart conditions such as atrial fibrillation?
2:10.8	How measuring a person's expo zone can identify what airborne pathogens they've been exposed to, and how Dr. Snyder is trying to determine what this means for disease risk?
2:19.8	How children exposed to high levels of air pollution have biomarkers of Alzheimer's disease in their brains?
2:25.8	How certain lifestyle of modifications such as sauna use and sulfuricane can help rid the body of some airborne pollutants?
2:32.8	How Dr. Snyder's data suggests that different organs such as the heart, liver, and kidneys age at different rates in different people?
	...

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