Welcome to Helix Talk, a podcast presented by the Rosalind Franklin University College of Pharmacy.

We're hoping that our real-life clinical pearls and discussions will help you stay up to date

and improve your pharmacy knowledge. This podcast contains general information for educational purposes only. This is

not professional advice and should not be used in lieu of obtaining advice from a qualified

health care provider. And now on to the show. Welcome to Helix Talk episode 37. I'm your

co-host Dr. Kane. And I'm Dr. Patel. Unfortunately, we don't have Dr. Schumann here today, but he'll be with us with a future

episode.

Today we're going to talk about a very controversial topic in something that should be a mastery

of pharmacist, and that is calculating creatin clearance, or how should we estimate the

renal function in general? And we'll talk more about this, but

Cretin clearance is one of those things that pharmacists do all the time

for drug dosing purposes.

And what we mean by that is that when we want to analyze someone's renal function,

we can estimate it using something called cratin clearance.

And obviously if a drug uses the kidney to be eliminated from the body, if your kidneys don't

work as well, then we have to make adjustments for that.

So if you have a really low cratin clearance, it means that you have a low renal function.

Maybe you don't need as much of a medication because that medication is going to stick

around longer.

And so you were saying, Dr. Kane, that the reason we teach students all the pharmacokinetic

and dynamic of medications and want them to know those parameters is because it is ultimately

resulting into the drug response based on how well the kidney function is, correct?

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