Hello, my friends. Today's podcast is with Dr. Dominic Dagestino, an assistant professor

at the University of South Florida in Tampa and an all-around expert on ketosis. I have

to warn you guys right now this is a fantastic podcast. In this podcast, Dominic discussed

Dom's efforts at teasing out the differences between induced nutritional ketosis through

a low carbohydrate high fat diet and ketosis from the dietary introduction of exogenous

ketones like beta hydroxybutyrate, especially in the context of therapeutic and performance

enhancing effects. His work on formulating ketone esters, the difference is intolerability

between medium chain triglyceride powders versus liquids, as well as the amount of supplemental

medium chain triglyceride a person would need to consume in order to achieve mild ketosis

without carbohydrate restriction. The difference is between different types of ketogenic

diets, the modified Actins diet which has been demonstrated to have similar efficacy

to the classical ketogenic diet and the treatment of drug-resistant epilepsy and how this

may be a slightly more practical option for achieving therapeutic nutritional ketosis.

The importance of making the correct carbohydrate choices, even and maybe especially in the

context of a ketogenic diet, with a diverse variety of raw vegetables being the most favorable.

What keto adaptation is and what it means at a physiological level to be keto adapted

and how this is distinguished from short periods of ketosis we experience in our day to day

lives. Some of Dom's ideas around cycling various dietary strategies as a way of promoting

metabolic flexibility, how ketones, when used as a source of energy, may result in a net

reduction in the number of damaging reactive byproducts known as reactive oxygen species,

than what may be produced by other forms of energy metabolism, while also producing more ATP

proportionately the same amount of oxygen. And so much more, oh my lord, there's so much more.

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